On 7 January, Wheatley Seniors Manav Bansal, Anya Chabria, Victor Li and Lucy Zha Shukla were named scholars in the 2021 Regeneron Science Talent Search!
In 2017, Regeneron became only the third sponsor (after Westinghouse and Intel) of the Science Talent Search, the nation’s oldest and most prestigious science and math competition for high school seniors. As part of its 10-year, $100 million commitment, Regeneron nearly doubled the overall award distribution to $3.1 million annually to better reward the best and brightest young minds. Founded and led by two Science Talent Search alumni, Regeneron recognizes and prioritizes the need to inspire more young people to engage in science.
The Regeneron Science Talent Search scholars were selected from 1,760 applications, which were received from 611 high schools across 49 states. The scholars were selected based on their exceptional research skills, commitment to academics, innovative thinking and promise as scientists.
Below you will find the project titles and a brief description for the projects conducted by our Regeneron Scholars!
Metformin and Mannose Inhibit Human Hepatic Stellate Cell Activation and Proliferation: Implications for Anti-Fibrotic Therapies in Patients with MPI Deficiency and Chronic Liver Disease
This project focused on a combination therapy for a congenital disorder of glycosylation that leads to scarring of the liver and ultimately, the need for a transplant in children. By targeting the proliferation and activation of the cells responsible for creating this scar tissue, known as the hepatic stellate cell, this research opens up the possibility for potential treatments to other liver diseases, such as Non-Alcoholic Fatty Liver Disease (NAFLD).
A New Look at Writing: Using Fractal Geometry to Evaluate Whether SLV Affects the Readability of Written Works
This project emphasizes the quantitative aspect of writing. Fractal complexity can be used as a measurement of sentence length variation (SLV). Using fractal geometry, this research bridges STEM and the humanities and considers whether SLV influences the ease of reading and enjoyability of reading a written work.
Acoustic Analysis of Laser-Induced Graphene: Development of Quantitative Indicators for Direct Determination of Quality and Microstructure Morphology
The development of a fast and inexpensive method for determining the quality of Laser-Induced Graphene. Unlike the current usage of scanning electron microscopy and Raman spectroscopy, the technique developed does not require sample preparation while being cost effective.
Investigating the Therapeutic Potential of Curcumin and Capsaicin: A Comparative Study on Neuroblastoma and Hypothalamic Cells
This study evaluates therapeutic potentials of curcumin and capsaicin in neuroblastoma, a common pediatric tumor, and hypothalamic cells. While they synergistically inhibit neuroblastoma cell growth, they also show toxicity in hypothalamic neurogenesis, raising caution to their clinical use on humans.
On January 21, 40 of the 300 scholars will be named Regeneron Science Talent Search finalists.
You can read Newsday’s coverage of Long Island’s scholars through this link: Regeneron Scholars in Newsday
You can view all of the 300 Regeneron Scholars here: STS 2021 Scholar Book
Congratulations to Manav, Anya, Victor and Lucy! Congratulations as well to Mr. Paulson, our Science Research Coordinator.
[Thanks to Mr. Paulson for the project write-ups.]